1-Piperidinecarboxylic acid, 4-(1-aMino-3-hydroxypropyl)-, 1,1-diMethylethyl ester - Names and Identifiers
1-Piperidinecarboxylic acid, 4-(1-aMino-3-hydroxypropyl)-, 1,1-diMethylethyl ester - Physico-chemical Properties
Molecular Formula | C13H26N2O3
|
Molar Mass | 258.36 |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
1-Piperidinecarboxylic acid, 4-(1-aMino-3-hydroxypropyl)-, 1,1-diMethylethyl ester - Introduction
1-BOC-4-1-amino-3-hydroxypropyl)-1-piperidine is an organic compound whose chemical name is tert-butyl 4-(5-1-hydroxypropyl) piperidine-1-carboxylate.
Nature:
1-BOC-4-(1-amino-3-hydroxypropyl)-1-piperidine is a colorless crystal, soluble in organic solvents such as methylene chloride, acetone and methanol. It is a stable compound with good stability to air and humidity at room temperature.
Use:
1-BOC-4-(1-amino-3-hydroxypropyl)-1-piperidine is an important organic synthesis intermediate. It can be used to synthesize a variety of drugs, such as anti-tumor drugs and antiviral drugs. In addition, it can also be used as a reagent and catalyst in chemical analysis.
Preparation Method:
1-BOC-4-(1-amino -3-hydroxypropyl)-1-piperidine is generally prepared by a substitution reaction with piperidine. Specifically, piperidine is first reacted with 3-chloropropanol to form 3-(piperidinyl) propanol, and then reacted with polymethyl carbonate (specifically, t-butyl dimethyl carbonate) to obtain the final product.
Safety Information:
1-BOC-4-(1-amino-3-hydroxypropyl)-1-piperidine is generally safe under routine operations, but the following matters still need to be paid attention:
-May be irritating, avoid contact with skin and eyes.
-During operation, care should be taken to avoid inhaling its dust or vapor.
-Keep away from flammable materials and high temperatures during storage and handling.
-Seek immediate medical help if exposure or inhalation causes discomfort or adverse reactions.
Last Update:2024-04-09 20:52:54